Lipid Controls
Medchemexpress LLC Dspe-peg2000-crgdkgpdc (disulfide bridge:Cys1-Cys9) | 95.0% | 2000 (Average) | 25 MG
DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and an αv-integrins targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and is then proteolytically cleaved in the tumor to produce CRGDK/R, which interacts with neuropilin-1. This compound has tumor-targeting and tumor-penetrating properties and can be used for agent delivery.
- Irgd peptide binds to αv-integrins.
- Proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1.
- Possesses tumor-targeting and tumor-penetrating properties.
- Can be used for agent delivery.
- Used to construct nanomicelles for targeted delivery of salinomycin to intervene in liver cancer cells and cancer stem cells.
- Used to construct a tumor-penetrating peptide liposome that exhibits antitumor effects, including a significant reduction in tumor volume and an increase in body weight and spleen index.
Cayman Chemical DLIn-MC4-DMA 50mg
An ionizable cationic lipid (pKa = 6.93); LNPs containing DLin-MC4-DMA and encapsulating siRNA for F7 reduce its gene expression levels in mice
Sigma Aldrich Fine Chemicals Biosciences 1-Stearoyl-sn-glycero-3-phosphocholine | 19420-57-6 | MFCD00050427 | 5mg
1-Stearoyl-sn-glycero-3-phosphocholine | Purity: ≥99% | Mol Wt: 523.68 | 19420-57-6 | MFCD00050427 | 5mg
Cayman Chemical Lyso-PAF C-18 1mg
Lyso-PAF C-18 can be formed by either the action of PAF-AH on PAF C-18{2626} or by the action of a CoA-independent transacylase on 1-O-octadecyl-2-acyl-glycerophosphocholine.{240,2098} Lyso PAF C-18 is a substrate for eitherPAF C-18 formation by the remodeling pathway{939} or selective acylation with arachidonic acid by a CoA-independent transacylase.{2101}
Cayman Chemical 1 2-DIoleoyl-sn-glycerol 10mg
An analog of the PKC-activating second messengers collectively called DAG; equipotent to 1,2-dioctanoyl-sn-glycerol in induction of the acrosome reaction in human sperm
Medchemexpress LLC HY-134781 5mg , CKK-E12 CAS:1432494-65-9 Purity:>98%
HY-134781 5mg CKK-E12 CAS: 1432494-65-9 CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based therapeutics. cKK-E12 was highly selective toward liver parenchymal cell in vivo, Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical 1 3DIoleoyl2Octnoyl Glyce 1mg
A triacylglycerol; been used to characterize the functionality of R. oryzae lipase for regiodistribution analysis of fats containing medium- and short-chain fatty acids
Medchemexpress LLC DLin-M-C4-DMA | 1226909-66-5 | C44H81NO2 | 5 MG
DLin-M-C4-DMA (Compound MC4) is a cationic lipid used for the delivery of nucleic acids.
- Cationic lipid
- Used for nucleic acid delivery
- Molecular weight: 656.12
- Appearance: Colorless to light yellow liquid
- Density: 0.886 g/cm³
Avanti Polar Lipids 4ME 16:0 (DPHPC), 200 MG
1,2-diphytanoyl-sn-glycero-3-phosphocholine. 207131-40-6
Avanti Polar Lipids 14:0 PC IN CHLOROFORM, 25MG
1,2-dimyristoyl-sn-glycero-3-phosphocholine. 18194-24-6
Cayman Chemical DLIn-KC2-DMA 5mg
An ionizable cationic lipid (pKa = 6.7); has been used in the formation of LNPs encapsulating siRNA or plasmid DNA for use in vitro and in vivo; LNPs containing DLin-KC2-DMA selectively accumulate in the liver after i.v. or i.m. administration in mice or localize to the retinal pigment epithelium and Müller glia after subretinal administration; DLin-KC2-DMA-containing LNPs encapsulating F7-targeted siRNA reduce serum Factor VII levels in mice; DLin-KC2-DMA-containing LNPs encapsulating AR-targeted siRNA decrease serum PSA and tumor androgen receptor levels in an LNCaP prostate cancer mouse xenograft model
Apexbio Technology LLC DSG-PEG 2000 500mg
DSG-PEG 2000 is a PEG-modified lipid that can be used with cationic lipids such as D-Lin-MC3-DMA (No A8791) to prepare cationic nanoparticles (LNP) capable of encapsulating and delivering siRNA mRNA DNA or small molecules into the cytoplasm
Cayman Chemical 1 3DIoleoyl2ElaIdoyl Glyce 1mg
A triacylglycerol; has been used to study the effects of unsaturation and sn-2 substitution on the polymorphic behavior of triacylglycerols